Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.78 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.78 |
| ▸ | BUB1 | O43683 | 1/20 | 0.66 |
| ▸ | PRKACG | P22612 | 1/20 | 0.66 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.66 |
| ▸ | ACSL5 | Q9ULC5 | 1/20 | 0.66 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424327 | 0.92 | MAPK14 (0.93) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3408283 | 0.91 | MAPK14 (0.91) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3407400 | 0.90 | MAPK14 (0.93) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3407363 | 0.88 | MAPK14 (1.00) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3410765 | 0.86 | MAPK14 (0.78) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL20448647 | 0.85 | MAPK14 (0.76) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3409067 | 0.84 | MAPK14 (0.82) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3408716 | 0.84 | MAPK14 (0.78) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3431414 | 0.82 | MAPK14 (0.82) | MAPK14CYP2C9MAPK11BUB1PRKACG | |
| SCHEMBL3405520 | 0.82 | MAPK14 (0.74) | MAPK14CYP2C9MAPK11BUB1PRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357916-A1 | BENZAMIDE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |