SCHEMBL20460809

SCHEMBL20460809

CC(=O)OCC1C[C@@H](CO)CN(C(=O)OCc2ccccc2)C1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP2C19 P33261 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HTR2C P28335 2/20 0.43
GRIN2B Q13224 4/20 0.42
HTT P42858 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
F13A1 P00488 1/20 0.39
TGM2 P21980 1/20 0.39
TGM1 P22735 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30994771 0.90 SMN1; SMN2 (0.56) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL14428303 0.90 SMN1; SMN2 (0.56) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL29333221 0.90 SMN1; SMN2 (0.56) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL3154275 0.85 SMN1; SMN2 (0.58) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL29080042 0.83 SMN1; SMN2 (0.51) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL21193584 0.82 MEN1 (0.43) SMN1; SMN2NPC1RAB9ACYP2C19MEN1
SCHEMBL14068102 0.81 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL21193505 0.79 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL21559813 0.78 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL100555 0.77 SMN1; SMN2 (0.64) SMN1; SMN2NPC1RAB9ACYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357908-B1 METHOD FOR PRODUCING ALDEHYDE COMPOUND OR KETONE COMPOUND FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-12-09 EP disclosed
EP-3357908-A1 METHOD FOR PRODUCING ALDEHYDE COMPOUND OR KETONE COMPOUND Fujifilm Finechemicals Co., Ltd. (JP) 2018-08-08 EP disclosed