Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 5/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | ITK | Q08881 | 3/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.42 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125675 | 0.92 | KDR (0.52) | USP30LCKPCSK9KDRITK | |
| SCHEMBL29470482 | 0.92 | KDR (0.52) | USP30LCKPCSK9KDRITK | |
| SCHEMBL29470541 | 0.92 | KDR (0.49) | USP30LCKPCSK9KDRITK | |
| SCHEMBL6125718 | 0.92 | KDR (0.49) | USP30LCKPCSK9KDRITK | |
| SCHEMBL8739542 | 0.92 | LCK (0.45) | USP30LCKPCSK9KDRITK | |
| SCHEMBL8739127 | 0.91 | KDR (0.51) | USP30LCKPCSK9KDRITK | |
| SCHEMBL15673350 | 0.89 | KDR (0.57) | USP30LCKKDRITKTBK1 | |
| SCHEMBL20055933 | 0.89 | KDR (0.47) | USP30LCKKDRTBK1 | |
| SCHEMBL29470441 | 0.89 | KDR (0.57) | LCKKDRTBK1 | |
| SCHEMBL15673237 | 0.89 | KDR (0.57) | LCKKDRTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357915-A1 | HETEROCYCLE AMINES WITH ANTI-INFLAMMATORY ACTIVITY | Ligand Pharmaceuticals Inc. (US) | 2018-08-08 | — | — | EP | disclosed |