Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20464846 | 0.85 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL20464842 | 0.85 | TSHR (0.58) | TSHRALDH1A1LMNATHRBTHRA | |
| SCHEMBL20464831 | 0.82 | ESR1 (0.60) | TSHRALDH1A1LMNATHRBTHRA | |
| SCHEMBL20464810 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464826 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464805 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464821 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464807 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464806 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL20464804 | 0.81 | TSHR (0.66) | TSHRALDH1A1LMNATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223120-A1 | THERMOCHROMIC COLOR-MEMORY COMPOSITION AND THERMOCHROMIC COLOR-MEMORY MICROCAPSULE PIGMENT ENCAPSULATING SAME | THE PILOT INK CO., LTD. (JP) | 2018-08-09 | — | — | US | disclosed |