SCHEMBL20471908

SCHEMBL20471908

Cc1cccc2c1ncn2Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.37
CYP17A1 P05093 5/20 0.36
PI4KA P42356 1/20 0.35
PI4K2B Q8TCG2 1/20 0.35
PI4K2A Q9BTU6 1/20 0.35
PI4KB Q9UBF8 1/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
PARP15 Q460N3 1/20 0.34
PARP10 Q53GL7 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
CYP1A2 P05177 2/20 0.34
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
PARP1 P09874 1/20 0.33
AURKA O14965 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128435 0.78 DDB1 (0.42) TLR8CYP17A1CYP1A2TSHRHTR1A
SCHEMBL15372298 0.76 CYP17A1 (0.39) TLR8CYP17A1PI4KAPI4K2BPI4K2A
SCHEMBL14879390 0.76 TLR8 (0.37) TLR8CYP17A1PI4KAPI4K2BPI4K2A
SCHEMBL3424861 0.76 PARP15 (0.38) TLR8CYP17A1CYP11B1CYP11B2PARP15
SCHEMBL6551451 0.76 CYP17A1 (0.36) TLR8CYP17A1CYP11B1CYP11B2PARP15
SCHEMBL3425500 0.76 CYP17A1 (0.36) TLR8CYP17A1CYP11B1CYP11B2PARP15
SCHEMBL19911312 0.74 CYP17A1 (0.35) TLR8CYP17A1CYP11B1CYP11B2PARP15
SCHEMBL4072933 0.73 PI4KA (0.39) CYP17A1PI4KAPI4K2BPI4K2API4KB
SCHEMBL17691571 0.73 HTT (0.56) CYP17A1
SCHEMBL19397177 0.73 SMN1; SMN2 (0.50) PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
WO-2018147626-A1 NOVEL HETEROCYCLIC COMPOUND, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2018-08-16 WO disclosed