SCHEMBL2047243

SCHEMBL2047243

C=CCC1(CC=CC)C(=O)N(Cc2ccccc2)C(=O)N(Cc2ccccc2)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.57
ELANE P08246 4/20 0.49
CTSG P08311 2/20 0.46
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
CMA1 P23946 1/20 0.46
CTRC Q99895 1/20 0.46
EP300 Q09472 4/20 0.41
PRTN3 P24158 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047241 1.00 NPSR1 (0.57) NPSR1ELANECTSGF2PLG
SCHEMBL2045025 0.90 NPSR1 (0.64) NPSR1ELANECTSGF2PLG
SCHEMBL2050387 0.86 ELANE (0.41) NPSR1ELANECTSGF2PLG
SCHEMBL2050388 0.86 ELANE (0.41) NPSR1ELANECTSGF2PLG
SCHEMBL2045781 0.86 CYP2C19 (0.47) NPSR1ELANECTSGF2PLG
SCHEMBL2045783 0.86 CYP2C19 (0.47) NPSR1ELANECTSGF2PLG
SCHEMBL2052865 0.79 ELANE (0.37) NPSR1ELANECTSGPRTN3KMT2A
SCHEMBL2052864 0.79 ELANE (0.37) NPSR1ELANECTSGPRTN3KMT2A
SCHEMBL2047369 0.78 ELANE (0.50) NPSR1ELANECYP2C19
SCHEMBL2047367 0.78 ELANE (0.50) NPSR1ELANECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed