Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 14/20 | 0.65 |
| ▸ | FER | P16591 | 6/20 | 0.62 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910806 | 1.00 | SYK (0.65) | SYKFERZAP70 | |
| SCHEMBL14928588 | 1.00 | SYK (0.65) | SYKFERZAP70 | |
| SCHEMBL16165261 | 0.91 | FER (0.60) | SYKFER | |
| SCHEMBL14910498 | 0.91 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL14909244 | 0.91 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL14909694 | 0.91 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL14909689 | 0.91 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL5027824 | 0.90 | SYK (0.59) | SYKFER | |
| SCHEMBL16164769 | 0.89 | FER (0.58) | SYKFER | |
| SCHEMBL14909145 | 0.89 | FER (0.78) | SYKFERZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |