SCHEMBL20473636

SCHEMBL20473636

NC(=O)c1cc(F)c(NC2CCCCC2N)nc1Nc1ccnc2c1ccn2CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14909804 1.00 SYK (0.52) SYK
SCHEMBL14929905 0.92 SYK (0.51) SYK
SCHEMBL14909568 0.92 SYK (0.51) SYK
SCHEMBL14911266 0.91 SYK (0.54) SYK
SCHEMBL14908844 0.91 SYK (0.54) SYK
SCHEMBL14923825 0.90 SYK (0.49) SYK
SCHEMBL14929896 0.90 SYK (0.49) SYK
SCHEMBL14908897 0.90 SYK (0.52) SYK
SCHEMBL14908896 0.90 SYK (0.52) SYK
SCHEMBL14909744 0.89 SYK (0.51) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2589592-B1 NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF FUJIFILM CORP (JP) 2018-08-22 — — EP disclosed
Send feedback