Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.85 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193647 | 1.00 | ALOX5AP (0.85) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL4192668 | 0.98 | ALOX5AP (0.81) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3469094 | 0.92 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL176475 | 0.92 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL168991 | 0.92 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3060242 | 0.91 | ALOX5AP (0.85) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3468699 | 0.90 | ALOX5AP (0.87) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL4188032 | 0.90 | ALOX5AP (0.96) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL4192902 | 0.89 | ALOX5AP (0.84) | ALOX5APALOX5CYP3A4CYP2C9 | |
| SCHEMBL3478677 | 0.89 | ALOX5AP (0.76) | ALOX5APALOX5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018152405-A1 | REDUCTION OF PRO-INFLAMMATORY HDL USING A LEUKOTRIENE INHIBITOR | AUTOIMMUNE PHARMA LLC (US) | 2018-08-23 | — | — | WO | disclosed |