Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169943 | 0.87 | ALOX5AP (1.00) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL20475100 | 0.84 | ALOX5AP (0.73) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL20475141 | 0.84 | ALOX5AP (0.78) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL169960 | 0.79 | ALOX5AP (0.85) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL2107903 | 0.79 | ALOX5AP (0.81) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL169878 | 0.78 | ALOX5AP (0.80) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL169793 | 0.77 | ALOX5AP (0.81) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL170095 | 0.77 | ALOX5AP (0.77) | ALOX5APCYP2C9CYP3A4CYP2D6PTGS1 | |
| SCHEMBL169407 | 0.76 | ALOX5AP (1.00) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 | |
| SCHEMBL23641171 | 0.76 | ALOX5AP (0.74) | ALOX5APCYP2C9CYP3A4CYP2D6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018152405-A1 | REDUCTION OF PRO-INFLAMMATORY HDL USING A LEUKOTRIENE INHIBITOR | AUTOIMMUNE PHARMA LLC (US) | 2018-08-23 | — | — | WO | claimed |