SCHEMBL20480720

SCHEMBL20480720

CCCCCCCCC(CCCCCC)COC(=O)C=Cc1ccc(OC)cc1

nearest known ligand 0.82

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.82
LMNA P02545 2/20 0.58
TAS1R3 Q7RTX0 4/20 0.55
TAS1R1 Q7RTX1 4/20 0.55
SMN1; SMN2 Q16637 1/20 0.52
GSK3B P49841 1/20 0.49
F3 P13726 1/20 0.48
APP P05067 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
THRB P10828 1/20 0.47
ATM Q13315 1/20 0.47
CASP3 P42574 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20480681 1.00 TDP1 (0.82) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
SCHEMBL1960360 0.95 TDP1 (0.91) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
SCHEMBL1960361 0.95 TDP1 (0.91) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
SCHEMBL9098850 0.95 TDP1 (0.91) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
SCHEMBL9098855 0.95 TDP1 (0.91) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
Octinoxate SCHEMBL15609 0.90 TDP1 (1.00) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
Octinoxate SCHEMBL39360 0.90 TDP1 (1.00) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
Octinoxate SCHEMBL15803545 0.90 TDP1 (1.00) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
Octinoxate SCHEMBL30252195 0.90 TDP1 (1.00) TDP1LMNATAS1R3TAS1R1SMN1; SMN2
Octinoxate SCHEMBL12533330 0.90 TDP1 (1.00) TDP1LMNATAS1R3TAS1R1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10620481-B2 Optical alignment film composition, optical alignment film, optical laminate, and image display device FUJIFILM CORPORATION (JP) 2020-04-14 US claimed
US-11518938-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20200399538-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-12-24 US disclosed
US-10620481-B2 Optical alignment film composition, optical alignment film, optical laminate, and image display device FUJIFILM CORPORATION (JP) 2020-04-14 US disclosed
US-20180246381-A1 OPTICAL ALIGNMENT FILM COMPOSITION, OPTICAL ALIGNMENT FILM, OPTICAL LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2018-08-30 US disclosed