Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.84 |
| ▸ | ATRIP | Q8WXE1 | 19/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482280 | 0.96 | ATR (0.92) | ATRATRIP | |
| SCHEMBL30140488 | 0.92 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501464 | 0.92 | ATR (1.00) | ATRATRIP | |
| SCHEMBL30140570 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501222 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL29397974 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501460 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL18109972 | 0.84 | ATR (1.00) | ATRATRIP | |
| SCHEMBL18110012 | 0.83 | ATR (1.00) | ATRATRIP | |
| SCHEMBL18109970 | 0.82 | ATR (1.00) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018153973-A1 | COMBINATION OF ATR KINASE INHIBITORS WITH PARP INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-08-30 | — | — | WO | disclosed |