Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.86 |
| ▸ | ATRIP | Q8WXE1 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17501484 | 0.93 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501635 | 0.92 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501209 | 0.85 | ATR (1.00) | ATRATRIP | |
| SCHEMBL18109965 | 0.85 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501616 | 0.84 | ATR (1.00) | ATRATRIP | |
| SCHEMBL23837809 | 0.83 | ATR (0.83) | ATRATRIP | |
| SCHEMBL30140481 | 0.83 | ATR (0.86) | ATRATRIP | |
| SCHEMBL17501487 | 0.83 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501324 | 0.83 | ATR (0.86) | ATRATRIP | |
| SCHEMBL23837808 | 0.83 | ATR (0.80) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018153969-A1 | COMBINATION OF ATR KINASE INHIBITORS WITH RADIUM-223 SALT | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-30 | — | — | WO | disclosed |