SCHEMBL20484692

SCHEMBL20484692

CC(C)[C@H](N)C(=O)N1C[C@H](O)C[C@H]1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 13/20 0.61
DPP8 Q6V1X1 9/20 0.61
DPP9 Q86TI2 8/20 0.61
DPP7 Q9UHL4 6/20 0.61
FAP Q12884 4/20 0.61
ATM Q13315 1/20 0.57
PIK3CD O00329 1/20 0.42
PREP P48147 2/20 0.41
PITRM1 Q5JRX3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20484694 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL30729252 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL30729264 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL4433716 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL4433719 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL4432649 0.89 ATM (0.56) DPP4DPP8DPP9DPP7FAP
SCHEMBL4432643 0.89 ATM (0.56) DPP4DPP8DPP9DPP7FAP
SCHEMBL4441243 0.87 ATM (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL15756825 0.87 ATM (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL4441246 0.87 ATM (0.61) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336654-A1 ANTIMICROBIAL PEPTIDOMIMETICS Universität Zürich (CH) 2024-10-10 US claimed
EP-4380689-A1 ANTIMICROBIAL PEPTIDOMIMETICS Basilea Pharmaceutica International AG, Allschwil (CH) 2024-06-12 EP claimed
CN-118043339-A Antimicrobial peptidomimetics 巴斯利尔药物阿尔施维尔国际股份公司 2024-05-14 CN claimed
EP-4214221-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP claimed
EP-4214220-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP claimed
WO-2023012319-A1 ANTIMICROBIAL PEPTIDOMIMETICS SPEXIS AG (CH) 2023-02-09 WO claimed
WO-2022028737-A1 ANTIMICROBIAL PEPTIDOMIMETICS POLYPHOR AG (CH) 2022-02-10 WO claimed
US-20240336654-A1 ANTIMICROBIAL PEPTIDOMIMETICS Universität Zürich (CH) 2024-10-10 US disclosed
CN-118043339-A Antimicrobial peptidomimetics 巴斯利尔药物阿尔施维尔国际股份公司 2024-05-14 CN disclosed
WO-2024029613-A1 HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF MUTANT KRAS PROTEIN アステラス製薬株式会社 2024-02-08 WO disclosed
EP-4214221-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP disclosed
EP-4214220-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP disclosed
WO-2023012319-A1 ANTIMICROBIAL PEPTIDOMIMETICS SPEXIS AG (CH) 2023-02-09 WO disclosed
WO-2022028737-A1 ANTIMICROBIAL PEPTIDOMIMETICS POLYPHOR AG (CH) 2022-02-10 WO disclosed
EP-3341007-B1 MALT1 INHIBITORS AND USES THEREOF UNIV CORNELL (US) 2020-12-23 EP disclosed
US-10711036-B2 MALT1 inhibitors and uses thereof CORNELL UNIVERSITY (US) 2020-07-14 US disclosed
US-20180251489-A1 MALT1 INHIBITORS AND USES THEREOF Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) 2018-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180251489-A1 MALT1 INHIBITORS AND USES THEREOF MALT1, BCL3, BCL6 DPP4 2275/4885DPP8 1924/4885DPP9 2057/4885
US-10711036-B2 MALT1 inhibitors and uses thereof MALT1, BCL3, BCL6 DPP4 2242/4885DPP8 1846/4885DPP9 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.