SCHEMBL2048484

SCHEMBL2048484

COCCCOP(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.60
LPAR2 Q9HBW0 6/20 0.60
LPAR1 Q92633 4/20 0.60
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.43
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
LPAR5 Q9H1C0 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576717 0.89 LPAR3 (0.64) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL2523093 0.84 LPAR3 (0.43) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL1514200 0.83
Hydrochloric Acid SCHEMBL27555558 0.83 LPAR3 (0.58) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL1574125 0.83 LPAR3 (0.71) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL15729175 0.82 SAT1 (0.52) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL12254989 0.82 SAT1 (0.52) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL27283647 0.81 LPAR3 (0.50) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
Ammonia Solution, Strong SCHEMBL27732597 0.81 LPAR3 (0.50) LPAR3LPAR2LPAR1CSNK2A2CSNK2B
SCHEMBL6033633 0.80 LPAR3 (0.76) LPAR3LPAR2LPAR1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396351-A1 COMPOUNDS AND METHODS FOR REDUCING DMPK EXPRESSION Ionis Pharmaceuticals, Inc. (US) 2024-07-10 EP claimed
WO-2023034868-A1 COMPOUNDS AND METHODS FOR REDUCING DMPK EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2023-03-09 WO claimed
US-20100022476-A1 PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2010-01-28 US claimed
EP-2337805-B2 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE MITSUI CHEMICALS INC (JP) 2025-06-18 EP disclosed
CN-119654413-A ITFG1 inhibitory nucleic acids 莱尔纳生物制药私人有限公司 2025-03-18 CN disclosed
CN-119452086-A GAPMER antisense oligonucleotides with modified backbone chemistry 奎里斯公司 2025-02-14 CN disclosed
WO-2025031485-A1 DSRNA MOLECULE INHIBITING HBV GENE EXPRESSION AND USE THEREOF 石药集团中奇制药技术(石家庄)有限公司 2025-02-13 WO disclosed
EP-4396351-A1 COMPOUNDS AND METHODS FOR REDUCING DMPK EXPRESSION Ionis Pharmaceuticals, Inc. (US) 2024-07-10 EP disclosed
EP-3129353-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2024-02-28 EP disclosed
CN-116802294-A Therapeutic agent for treating neurodegenerative disease UCL商业有限公司 2023-09-22 CN disclosed
WO-2023106258-A1 POLYMERIZABLE COMPOSITION FOR MANUFACTURING MOLDED ARTICLE, MOLDED ARTICLE AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2023-06-15 WO disclosed
WO-2015155367-A1 COMPOSITION CONTAINING AROMATIC NITRILES FOR THE PRODUCTION OF TRANSPARENT POLYTHIOURETHANE BODIES BAYER MATERIALSCIENCE AG (DE) 2015-10-15 WO disclosed
EP-2337805-B1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2014-12-17 EP disclosed
US-8829147-B2 Polymerizable liquid composition and process for the production of organic glass starting from polymerizable liquid compositions of the polyurethane type ACOMON AG (CH) 2014-09-09 US disclosed
EP-2571914-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX Mitsui Chemicals, Inc. (JP) 2013-03-27 EP disclosed
WO-2011144995-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX ACOMON AG (CH) 2011-11-24 WO disclosed
US-20110251301-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2011-10-13 US disclosed
EP-2337805-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2011-06-29 EP disclosed
WO-2010043392-A1 POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE ACOMON AG (CH) 2010-04-22 WO disclosed
US-20100022476-A1 PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022476-A1 PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER CCNI, MKI67, TP53 LPAR3 2807/4885LPAR2 4186/4885LPAR1 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.