Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 12/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336019 | 0.88 | ITGAV (0.42) | ITGAVITGB6GPR119 | |
| SCHEMBL20481267 | 0.88 | ITGAV (0.42) | ITGAVITGB6GPR119 | |
| SCHEMBL20481266 | 0.88 | ITGAV (0.42) | ITGAVITGB6GPR119 | |
| SCHEMBL28334820 | 0.87 | ITGAV (0.44) | ITGAVITGB6KMT2ALMNAMAPK1 | |
| SCHEMBL21767609 | 0.87 | ITGAV (0.41) | ITGAVITGB6GPR119 | |
| SCHEMBL21767607 | 0.87 | ITGAV (0.41) | ITGAVITGB6GPR119 | |
| SCHEMBL28565965 | 0.86 | ITGAV (0.43) | ITGAVITGB6KMT2ALMNAMAPK1 | |
| SCHEMBL21767721 | 0.85 | ITGAV (0.42) | ITGAVITGB6GPR119 | |
| SCHEMBL21767722 | 0.85 | ITGAV (0.42) | ITGAVITGB6GPR119 | |
| SCHEMBL17629333 | 0.84 | ITGAV (0.41) | ITGAVITGB6MAPK1P2RY12NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018160521-A2 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Lazuli, Inc. (US) | 2018-09-07 | — | — | WO | disclosed |