Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.55 |
| ▸ | ITGB6 | P18564 | 14/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487145 | 0.91 | ITGAV (0.55) | ITGAVITGB6ITGB3ITGB5 | |
| SCHEMBL20481057 | 0.87 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL30335970 | 0.87 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL20480998 | 0.86 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL30335732 | 0.86 | ITGAV (0.61) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL21317501 | 0.85 | ITGAV (0.67) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL7403635 | 0.82 | ITGAV (0.58) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL21777433 | 0.82 | ITGAV (0.54) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL21777434 | 0.82 | ITGAV (0.54) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL20481166 | 0.82 | ITGAV (0.59) | ITGAVITGB6ITGB3ITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018160521-A2 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Lazuli, Inc. (US) | 2018-09-07 | — | — | WO | disclosed |
| WO-2018160522-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Lazuli, Inc. (US) | 2018-09-07 | — | — | WO | disclosed |