SCHEMBL2048868

SCHEMBL2048868

CCCCCCCCCCCCCCCCCCOC(=O)CCc1cc(C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.49
GAA P10253 3/20 0.46
KMT2A Q03164 2/20 0.46
DGKA P23743 1/20 0.43
CNR2 P34972 4/20 0.43
ALDH1A1 P00352 2/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
CNR1 P21554 3/20 0.41
NAAA Q02083 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491336 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL17491367 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL284525 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL283818 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL17491170 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL17491358 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL283674 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL667600 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL284545 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2
SCHEMBL283571 1.00 ESR1 (0.49) ESR1GAAKMT2ADGKACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137540-B1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC IND INC (US) 2024-10-30 EP claimed
CN-116745353-A Compositions and methods for protecting organic polymeric materials from the deleterious effects of UV-C light exposure 塞特工业公司 2023-09-12 CN claimed
CN-112912442-B Copolyetherester formulation with improved thermal stability 杜邦聚合物公司 2023-06-20 CN claimed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP claimed
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. 2022-07-07 US claimed
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM CYTEC TECHNOLOGY CORP. 2022-05-19 US claimed
CN-114085468-A Solvent-resistant ABS composite material suitable for blow molding and preparation method thereof 安徽江淮汽车集团股份有限公司 2022-02-25 CN claimed
US-10975278-B2 Granular stabilizer compositions for use in polymer resins and methods of making same CYTEC INDUSTRIES INC. (US) 2021-04-13 US claimed
EP-2652014-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2020-07-01 EP claimed
US-10407563-B2 Processes for producing molded articles stabilized against ultraviolet light and thermal degradation CYTEC INDUSTRIES INC. (US) 2019-09-10 US claimed
WO-2013188490-A1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECHNOLOGY CORP. (US) 2013-12-19 WO claimed
US-8501846-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2013-08-06 US claimed
US-20130145962-A1 Stabilizer Compositions Containing Substituted Chroman Compounds and Methods of Use CYTEC TECHNOLOGY CORP. (US) 2013-06-13 US claimed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US claimed
US-20100256266-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US claimed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US claimed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US claimed
US-5081170-A Polyolefin, phenolic antioxidant, light stabilizer, sulfur antioxidant, talc filler, weatherproofing ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1992-01-14 US claimed
EP-0069702-B1 STOP CHAIN AGENT FOR VINYLCHLORIDE POLYMERISATION CIBA-GEIGY AG (CH) 1985-06-05 EP claimed
EP-0069702-A2 Stop chain agent for vinylchloride polymerisation CIBA-GEIGY AG (CH) 1983-01-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING RPS7, MRPS27, F7 ESR1 4567/4885GAA 1545/4885KMT2A 3197/4885
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM NOTUM, PMM2, WASF2 ESR1 4174/4885GAA 905/4885KMT2A 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.