SCHEMBL20489362

SCHEMBL20489362

CC(=O)c1cc(C(=O)NC(Cc2ccc(-c3cc(Cl)ccc3F)cc2)CC(O)C(=O)O)n[nH]1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MME P08473 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17011189 1.00 MME (0.65) MME
SCHEMBL20489361 0.91 MME (0.74) MME
SCHEMBL17011190 0.91 MME (0.74) MME
SCHEMBL22619585 0.86 MME (0.75) MME
SCHEMBL17011192 0.86 MME (0.75) MME
SCHEMBL16930701 0.85 MME (0.82) MME
SCHEMBL16930425 0.82 MME (0.71) MME
SCHEMBL16975155 0.82 MME (0.71) MME
SCHEMBL16975143 0.82 MME (0.71) MME
SCHEMBL16930528 0.82 MME (0.71) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3199517-B1 NEPRILYSIN INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2018-09-12 EP disclosed