SCHEMBL20489671

SCHEMBL20489671

CCS(=O)(=O)c1cc(OCOC)cnc1-c1nc2cc(SC(F)(F)F)ccc2o1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ UTRN P46939 7/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ MAPT P10636 3/20 0.32
▸ F2RL3 Q96RI0 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ POLB P06746 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ CEPT1 Q9Y6K0 1/20 0.31
▸ HSPD1 P10809 1/20 0.31
▸ HSPE1 P61604 1/20 0.31
▸ HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29603320 1.00 UTRN (0.35) UTRNCYP1A2AHRHDAC6SMN1; SMN2
SCHEMBL18760194 0.87 UTRN (0.32) UTRNCYP1A2AHRHDAC6
SCHEMBL23120266 0.84 UTRN (0.36) UTRNCYP1A2AHRHDAC6SMN1; SMN2
SCHEMBL29431627 0.84 UTRN (0.38) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL15858543 0.84 UTRN (0.38) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL29543511 0.84 UTRN (0.36) UTRNCYP1A2AHRHDAC6SMN1; SMN2
SCHEMBL21051275 0.84 UTRN (0.33) UTRNCYP1A2AHRHDAC6MAPT
SCHEMBL20489570 0.84 UTRN (0.33) UTRNSMN1; SMN2MAPTF2RL3POLB
SCHEMBL29603696 0.84 UTRN (0.33) UTRNSMN1; SMN2MAPTF2RL3POLB
SCHEMBL21051271 0.83 UTRN (0.35) UTRNCYP1A2AHRHDAC6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787809-B2 Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide NIHON NOHYAKU CO., LTD. (JP) 2023-10-17 — — US disclosed
EP-3372595-B1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALTS THEREOF AND AGRICULTURAL AND HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME NIHON NOHYAKU CO LTD (JP) 2023-06-28 — — EP disclosed
CN-110114354-B Condensed heterocyclic compound having oxime group or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2022-04-29 — — CN disclosed
US-20210371424-A1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2021-12-02 — — US disclosed
EP-3564238-B1 FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUNDS, AND METHOD FOR USING SAID INSECTICIDE NIHON NOHYAKU CO LTD (JP) 2021-10-13 — — EP disclosed
US-10856548-B2 Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide NIHON NOHYAKU CO., LTD. (JP) 2020-12-08 — — US disclosed
US-20200085054-A1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2020-03-19 — — US disclosed
EP-3564238-A1 FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUNDS, AND METHOD FOR USING SAID INSECTICIDE Nihon Nohyaku Co., Ltd. (JP) 2019-11-06 — — EP disclosed
EP-3372595-A1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALTS THEREOF AND AGRICULTURAL AND HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME Nihon Nohyaku Co., Ltd. (JP) 2018-09-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200085054-A1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE OXSR1, CBR3, OSR1 UTRN 4859/4885CYP1A2 186/4885AHR 956/4885
US-10856548-B2 Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide OXSR1, CBR3, OSR1 UTRN 4859/4885CYP1A2 186/4885AHR 956/4885
US-20210371424-A1 OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE DDT, OXSR1, ODC1 UTRN 4830/4885CYP1A2 135/4885AHR 619/4885
US-11787809-B2 Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide DDT, OXSR1, ODC1 UTRN 4830/4885CYP1A2 135/4885AHR 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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