Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20495013 | 1.00 | GBA1 (0.44) | GBA1MAPTSIGMAR1HDAC11SPHK2 | |
| SCHEMBL20494682 | 1.00 | GBA1 (0.44) | GBA1MAPTSIGMAR1HDAC11SPHK2 | |
| SCHEMBL25409395 | 0.86 | — | — | |
| SCHEMBL25409556 | 0.86 | — | — | |
| SCHEMBL25411772 | 0.86 | — | — | |
| SCHEMBL20494275 | 0.85 | MAPT (0.40) | GBA1MAPTSIGMAR1 | |
| SCHEMBL20494808 | 0.85 | MAPT (0.40) | GBA1MAPTSIGMAR1 | |
| SCHEMBL20494206 | 0.85 | MAPT (0.40) | GBA1MAPTSIGMAR1 | |
| SCHEMBL20495184 | 0.85 | MAPT (0.40) | GBA1MAPTSIGMAR1 | |
| SCHEMBL19910779 | 0.85 | MAPT (0.43) | MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018165614-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-09-13 | — | — | WO | disclosed |