⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325080 | 0.69 | — | — | |
| SCHEMBL19785546 | 0.69 | — | — | |
| SCHEMBL28228897 | 0.65 | CSNK2A1 (0.33) | — | |
| SCHEMBL28487092 | 0.65 | — | — | |
| SCHEMBL21590222 | 0.65 | — | — | |
| SCHEMBL30901481 | 0.65 | — | — | |
| SCHEMBL18527192 | 0.65 | — | — | |
| Formaldehyde SCHEMBL29160531 | 0.63 | — | — | |
| SCHEMBL30529349 | 0.61 | — | — | |
| SCHEMBL28235234 | 0.61 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-111699185-A | 6-azaindole compounds | 百时美施贵宝公司 | 2020-09-22 | — | — | CN | disclosed |
| WO-2018169700-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-09-20 | — | — | WO | disclosed |