Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606604 | 1.00 | HRH4 (0.67) | HRH4HRH3KCNH2 | |
| SCHEMBL12268328 | 1.00 | HRH4 (0.67) | HRH4HRH3KCNH2 | |
| SCHEMBL606605 | 1.00 | HRH4 (0.67) | HRH4HRH3KCNH2 | |
| SCHEMBL603494 | 0.83 | HRH4 (0.74) | HRH4HRH3KCNH2 | |
| SCHEMBL607455 | 0.83 | HRH4 (0.77) | HRH4HRH3KCNH2 | |
| SCHEMBL604327 | 0.83 | HRH4 (0.77) | HRH4HRH3KCNH2 | |
| SCHEMBL604357 | 0.81 | HRH4 (0.53) | HRH4HRH3 | |
| SCHEMBL603075 | 0.81 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL603076 | 0.81 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL603036 | 0.81 | HRH4 (1.00) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3378476-A1 | H4 RECEPTOR INHIBITORS FOR TREATING TINNITUS | Sensorion (FR) | 2018-09-26 | — | — | EP | disclosed |