⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464579 | 1.00 | EPHX1 (0.46) | — | |
| SCHEMBL23735487 | 0.93 | EPHX2 (0.56) | — | |
| SCHEMBL28580041 | 0.91 | EPHX1 (0.41) | — | |
| SCHEMBL13698908 | 0.91 | EPHX1 (0.55) | — | |
| SCHEMBL17407561 | 0.91 | EPHX2 (0.60) | — | |
| SCHEMBL12385850 | 0.91 | EPHX1 (0.55) | — | |
| SCHEMBL18814222 | 0.91 | ATM (0.45) | — | |
| SCHEMBL5949945 | 0.91 | EPHX1 (0.55) | — | |
| SCHEMBL22311485 | 0.91 | EPHX2 (0.60) | — | |
| SCHEMBL12513461 | 0.91 | ATM (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | claimed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | claimed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | claimed |
| EP-4698224-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2026-02-25 | — | — | EP | disclosed |
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-119241588-A | Sulfonamide compound for treatment and enantiomer thereof, preparation method and application | 华创合成制药股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2024218268-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2024-10-24 | — | — | WO | disclosed |
| EP-4440622-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2024-10-09 | — | — | EP | disclosed |
| US-12109207-B2 | Methods of using 4(1H)-quinolone derivatives | ACADEMIA SINICA (TW) | 2024-10-08 | — | — | US | disclosed |
| CN-118638025-A | Process for preparing (S) -4, 5-diamino-5-oxopentanoic acid tert-butyl ester | 细胞基因公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-1426365-A1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | Sankyo Agro Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-0923562-B1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | disclosed |