Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | FES | P07332 | 1/20 | 0.30 |
| ▸ | FER | P16591 | 1/20 | 0.30 |
| ▸ | MARK3 | P27448 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947383 | 1.00 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| Hydrochloric Acid SCHEMBL3142422 | 0.99 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| Hydrochloric Acid SCHEMBL3142414 | 0.99 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| Hydrochloric Acid SCHEMBL8327819 | 0.90 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| Hydrochloric Acid SCHEMBL8327814 | 0.90 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL8328790 | 0.89 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8328789 | 0.89 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8326429 | 0.87 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8326431 | 0.87 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8332314 | 0.86 | CA1 (0.32) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076946-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALZHEIMER | Universidad Del País Vasco (ES) | 2011-06-30 | — | — | WO | claimed |
| US-7750024-B2 | Remedy for glioblastoma | ASTELLAS PHARMA INC. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-20050165009-A1 | Remedy for glioblastoma | ASTELLAS PHARMA INC. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-0529636-B1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1999-06-23 | — | — | EP | disclosed |
| US-5436250-A | Isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1995-07-25 | — | — | US | disclosed |
| US-5242918-A | Isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-07 | — | — | US | disclosed |
| WO-1993005043-A1 | NOVEL ISATINOXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1993-03-18 | — | — | WO | disclosed |
| EP-0529636-A1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165009-A1 | Remedy for glioblastoma | GRM2, GRM1, GRM3 | GRIA1 17/4885GRIA2 19/4885GRIA3 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.