⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508352 | 1.00 | — | — | |
| SCHEMBL3321855 | 0.82 | — | — | |
| SCHEMBL3321852 | 0.82 | — | — | |
| SCHEMBL1570075 | 0.82 | — | — | |
| SCHEMBL4093231 | 0.72 | — | — | |
| SCHEMBL10723942 | 0.69 | — | — | |
| SCHEMBL1064989 | 0.69 | — | — | |
| SCHEMBL77706 | 0.69 | — | — | |
| SCHEMBL21840885 | 0.67 | — | — | |
| SCHEMBL8708711 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158343-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2024-05-16 | — | — | US | disclosed |
| CN-117534595-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116785269-A | Homotaurine derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230295079-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-4243802-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES FOR THE TREATMENT OF CEREBROVASCULAR DISEASE | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-09-20 | — | — | EP | disclosed |
| CN-116763768-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116059192-A | Use of isotopically enriched 3-amino-1-propanesulfonic acid and derivatives thereof | 润佳（苏州）医药科技有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-112791078-B | Use of isotopically enriched 3-amino-1-propanesulfonic acid and derivatives thereof | 润佳（苏州）医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114805211-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives, pharmaceutical compositions and uses thereof | 润佳（苏州）医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20220202778-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES FOR THE TREATMENT OF CEREBROVASCULAR DISEASE | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-30 | — | — | US | disclosed |
| WO-2022099412-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES FOR THE TREATMENT OF CEREBROVASCULAR DISEASE | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-05-19 | — | — | WO | disclosed |
| CN-108623501-B | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and their use | 润佳（苏州）医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-20210347731-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2021-11-11 | — | — | US | disclosed |
| CN-112791078-A | Use of isotopically enriched 3-amino-1-propanesulfonic acid and derivatives thereof | 润佳（苏州）医药科技有限公司 | 2021-05-14 | — | — | CN | disclosed |
| US-10954188-B2 | Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2021-03-23 | — | — | US | disclosed |
| US-20200223793-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) | 2020-07-16 | — | — | US | disclosed |
| EP-3601223-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2020-02-05 | — | — | EP | disclosed |
| US-10472323-B2 | Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2019-11-12 | — | — | US | disclosed |
| WO-2018170590-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2018-09-27 | — | — | WO | disclosed |
| US-20180273471-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | RISEN (SUZHOU) PHARMA TECH CO. LTD (CN) | 2018-09-27 | — | — | US | disclosed |