SCHEMBL20514347

SCHEMBL20514347

O=CC(O)C(O)COP(=O)(O)O.O=CC(O)COP(=O)(O)O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.85
PGD P52209 3/20 0.47
PGK1 P00558 1/20 0.41
PGK2 P07205 1/20 0.41
S1PR4 O95977 2/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
S1PR5 Q9H228 2/20 0.34
S1PR2 O95136 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TSPO P30536 1/20 0.34
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
LPAR6 P43657 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR4 Q99677 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
ENPP2 Q13822 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50110 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
SCHEMBL2619121 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
SCHEMBL18341437 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
SCHEMBL20455494 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
SCHEMBL2862562 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
SCHEMBL891659 0.92 MPI (1.00) MPIPGDPGK1PGK2S1PR4
Phosphoric Acid SCHEMBL28420442 0.90 MPI (0.96) MPIPGDPGK1PGK2S1PR4
Phosphoric Acid SCHEMBL5613914 0.90 MPI (0.96) MPIPGDPGK1PGK2S1PR4
SCHEMBL6040131 0.90 MPI (0.69) MPIPGDPGK1PGK2S1PR4
SCHEMBL328992 0.88 MPI (0.63) MPIPGDPGK1PGK2LPAR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3460069-B1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE GREENLIGHT BIOSCIENCES INC (US) 2021-10-20 EP disclosed
EP-3460069-A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE Greenlight Biosciences, Inc. (US) 2019-03-27 EP disclosed
EP-2885411-B1 MEANS AND METHODS FOR ALTERING THE LIGNIN PATHWAY IN PLANTS VIB VZW (BE) 2018-12-05 EP disclosed
EP-3030671-B1 ENGINEERED PROTEINS WITH A PROTEASE CLEAVAGE SITE GREENLIGHT BIOSCIENCES INC (US) 2018-10-03 EP disclosed