Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16876566 | 1.00 | SYK (0.52) | SYK | |
| SCHEMBL16876519 | 0.92 | SYK (0.57) | SYK | |
| SCHEMBL20514372 | 0.92 | SYK (0.57) | SYK | |
| SCHEMBL20514414 | 0.91 | SYK (0.56) | SYK | |
| SCHEMBL16876385 | 0.91 | SYK (0.56) | SYK | |
| SCHEMBL20514674 | 0.90 | SYK (0.57) | SYK | |
| SCHEMBL16875981 | 0.90 | SYK (0.57) | SYK | |
| SCHEMBL16876515 | 0.89 | SYK (0.58) | SYK | |
| SCHEMBL16876166 | 0.89 | SYK (0.58) | SYK | |
| SCHEMBL16876029 | 0.89 | SYK (0.58) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2863914-B1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME (US) | 2018-10-03 | — | — | EP | disclosed |