Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM6A | O15550 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074892 | 0.84 | EGFR (0.32) | PIM1 | |
| SCHEMBL10075151 | 0.84 | KDM4E (0.42) | KDM4EEGLN1LMNAMEN1KMT2A | |
| SCHEMBL10074597 | 0.81 | GSK3B (0.50) | EGLN1L3MBTL1LMNAHTTKMT2A | |
| SCHEMBL16431381 | 0.79 | SELL (0.52) | SELLSELPKDM4AKDM4EKDM6B | |
| SCHEMBL10074890 | 0.79 | SMN1; SMN2 (0.37) | PIM1ALDH1A1ALOX12MEN1HTT | |
| SCHEMBL20514738 | 0.78 | ERN1 (0.40) | SELLSELPKDM4AKDM4EKDM6B | |
| SCHEMBL10074406 | 0.77 | NPC1 (0.46) | — | |
| SCHEMBL16968748 | 0.76 | — | — | |
| SCHEMBL10075148 | 0.74 | SELL (0.41) | SELLSELPKDM4AKDM4EKDM6B | |
| SCHEMBL16968747 | 0.73 | KMT2A (0.42) | KDM4AEGLN1PIM1ALDH1A1EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655334-B1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS INC (US) | 2018-10-03 | — | — | EP | claimed |