Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.42 |
| ▸ | ATIC | P31939 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 4/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052180 | 1.00 | TTR (0.66) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL313372 | 0.98 | TTR (0.68) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL30322685 | 0.98 | TTR (0.68) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL9274363 | 0.97 | TTR (0.66) | TTRAURKAAURKBCYP1A2SENP2 | |
| Nitrogen SCHEMBL27709748 | 0.95 | TTR (0.64) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL9056262 | 0.88 | TTR (0.55) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL8497445 | 0.87 | TTR (0.53) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL8968585 | 0.85 | TTR (0.51) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL9274353 | 0.85 | TTR (0.60) | TTRAURKAAURKBCYP1A2SENP2 | |
| SCHEMBL10900215 | 0.84 | TTR (0.61) | TTRAURKAAURKBSENP2SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018177863-A1 | DERIVATIVES OF THE DISODIUM 2,2'-{CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(1-METHYL-1H-PYRROLE-4,2-DIYL) CARBONYLIMINO]}DINAPHTHALENE-1,5-DISULFONATE SALT AND RELATED COMPOUNDS AS HEPARANASE INHIBITORS FOR THE TREATMENT OF CANCER | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | disclosed |
| EP-3381897-A1 | DERIVATIVES OF THE DISODIUM 2,2'-{CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(1-METHYL-1H-PYRROLE-4,2-DIYL)CARBONYLIMINO]}DINAPHTHALENE-1,5-DISULFONATE SALT AND RELATED COMPOUNDS AS HEPARANASE INHIBITORS FOR THE TREATMENT OF CANCER | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | disclosed |
| CN-105612146-A | Arylsulfonic acid compound, use thereof, and method for producing arylsulfonic acid compound | NISSAN CHEMICAL IND LTD | 2016-05-25 | — | — | CN | disclosed |