Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514959 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1HTTALDH1A1MME | |
| SCHEMBL9386073 | 0.86 | KMT2A (0.55) | SMN1; SMN2L3MBTL1HTTALDH1A1NAALAD2 | |
| SCHEMBL6136662 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1HTTALDH1A1LMNA | |
| SCHEMBL6136656 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1HTTALDH1A1LMNA | |
| SCHEMBL6136290 | 0.85 | FNTA (0.60) | SMN1; SMN2L3MBTL1HTTALDH1A1SIGMAR1 | |
| SCHEMBL6136285 | 0.85 | FNTA (0.60) | SMN1; SMN2L3MBTL1HTTALDH1A1SIGMAR1 | |
| SCHEMBL6136282 | 0.85 | FNTA (0.60) | SMN1; SMN2L3MBTL1HTTALDH1A1SIGMAR1 | |
| SCHEMBL6567538 | 0.81 | NAALAD2 (0.66) | NAALAD2MEN1KMT2A | |
| SCHEMBL27694707 | 0.81 | NAALAD2 (0.66) | NAALAD2MEN1KMT2A | |
| SCHEMBL6567542 | 0.81 | NAALAD2 (0.66) | NAALAD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381898-A1 | SYMMETRICAL TRIS-ARYL-AMIDE DERIVATIVES AND THEIR USE AS ANTI-HEPARANASE | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | disclosed |