Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.34 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561645 | 0.77 | HSP90AB1 (0.42) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL16376659 | 0.75 | CYP2C19 (0.47) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL6993376 | 0.74 | P2RY6 (0.41) | KDM4EHSD17B10DNMT3BALDH1A1 | |
| SCHEMBL28144298 | 0.74 | HPGD (0.40) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL31561626 | 0.70 | NPSR1 (0.39) | KDM4EHSD17B10HSP90AB1HPGDTSHR | |
| SCHEMBL2977413 | 0.69 | KDM4E (0.40) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL28057067 | 0.69 | MAOB (0.36) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL27532834 | 0.68 | CYP3A4 (0.49) | MAOBADORA3ARCYP19A1HSP90AB1 | |
| SCHEMBL403523 | 0.68 | MAOB (0.65) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL32498549 | 0.68 | MAOB (0.65) | MAOBKDM4EHSD17B10ADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10682359-B2 | Inhibitors of glucose kinases, along with methods of their formation and use | UNIVERSITY OF SOUTH CAROLINA (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180280404-A1 | Inhibitors of Glucose Kinases, Along with Methods of Their Formation and Use | UNIVERSITY OF SOUTH CAROLINA | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180280404-A1 | Inhibitors of Glucose Kinases, Along with Methods of Their Formation and Use | GCK, GCKR, GALK1 | MAOB 3334/4885KDM4E 911/4885HSD17B10 2521/4885 |
| US-10682359-B2 | Inhibitors of glucose kinases, along with methods of their formation and use | GCK, GCKR, GALK1 | MAOB 3334/4885KDM4E 911/4885HSD17B10 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.