SCHEMBL20520177

CC(=O)NC1C(O)[C@H](O[C@@H]2OC(CO)[C@H](O)C(O[C@H]3OC(CO)[C@H](O)C(O)C3O)C2O)C(CO)O[C@H]1OCCCNC(=O)CCOCCOCCOCCOCCNC(=O)COc1cc(OCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCO[C@@H]2OC(CO)[C@@H](O[C@@H]3OC(CO)[C@H](O)C(O[C@H]4OC(CO)[C@H](O)C(O)C4O)C3O)C(O)C2NC(C)=O)cc(C(=O)NCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@@H]32)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	MDK	P21741	4/20	0.64

▸	FGF1	P05230	1/20	0.55

▸	FGF2	P09038	1/20	0.55

▸	VEGFA	P15692	1/20	0.55

▸	HPSE	Q9Y251	1/20	0.55

▸	CSNK2A2	P19784	1/20	0.45

▸	CSNK2B	P67870	1/20	0.45

▸	CSNK2A1	P68400	1/20	0.45

▸	CAMK2B	Q13554	1/20	0.45

▸	FOLH1	Q04609	7/20	0.43

▸	PRSS1	P07477	2/20	0.43

▸	PRSS2	P07478	2/20	0.43

▸	PRSS3	P35030	2/20	0.43

▸	TPSAB1	Q15661	2/20	0.43

▸	F2	P00734	1/20	0.43

▸	PKM	P14618	2/20	0.41

▸	HSP90AB1	P08238	1/20	0.40

▸	LGALS8	O00214	1/20	0.40

▸	LGALS3	P17931	1/20	0.40

▸	LGALS4	P56470	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20520078	1.00	MDK (0.64)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20519931	0.98	MDK (0.62)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20519905	0.98	MDK (0.62)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20520123	0.98	MDK (0.61)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL23126137	0.96	HPSE (0.58)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20520126	0.95	MDK (0.60)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20519810	0.95	MDK (0.60)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20519819	0.95	MDK (0.60)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20520046	0.95	MDK (0.62)	MDKFGF1FGF2VEGFAHPSE
SCHEMBL20520041	0.95	MDK (0.62)	MDKFGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20210369850-A1	COMPOUNDS AND THERAPEUTIC USES THEREOF	Centauri Therapeutics Limited (GB/GB) (GB)	2021-12-02	—	—	US	disclosed
US-10953100-B2	Compounds and therapeutic uses thereof	CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB)	2021-03-23	—	—	US	disclosed
US-20180280521-A1	COMPOUNDS AND THERAPEUTIC USES THEREOF	CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB)	2018-10-04	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20210369850-A1	COMPOUNDS AND THERAPEUTIC USES THEREOF	CD47, MYD88, NFATC1	MDK 2412/4885FGF1 4232/4885FGF2 4081/4885
US-10953100-B2	Compounds and therapeutic uses thereof	CD47, MYD88, NFATC1	MDK 2412/4885FGF1 4232/4885FGF2 4081/4885
US-20180280521-A1	COMPOUNDS AND THERAPEUTIC USES THEREOF	CD47, MYD88, NFATC1	MDK 2412/4885FGF1 4232/4885FGF2 4081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.