SCHEMBL20520237

SCHEMBL20520237

CCCCCCCCCCCCCCCCCCCCCC(c1ccccc1O)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
CSNK1E P49674 1/20 0.45
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
NAAA Q02083 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20520201 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520273 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520222 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520257 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520293 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520227 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520238 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520230 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL20520279 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2
SCHEMBL9166981 1.00 TSHR (0.50) TSHRGABRA1GABRB2CSNK1ECYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3640278-B1 AROMATIC POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME, AND AROMATIC DIHYDROXY COMPOUND MITSUBISHI CHEM CORP (JP) 2022-11-09 EP disclosed
EP-3388465-B1 FLUIDITY MODIFIER FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME MITSUBISHI CHEM CORP (JP) 2022-09-14 EP disclosed
US-11326023-B2 Aromatic polycarbonate resin, method for producing same, and aromatic dihydroxy compound MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-10 US disclosed
EP-3640278-A1 AROMATIC POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME, AND AROMATIC DIHYDROXY COMPOUND Mitsubishi Chemical Corporation (JP) 2020-04-22 EP disclosed
US-20200115494-A1 AROMATIC POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME, AND AROMATIC DIHYDROXY COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2020-04-16 US disclosed
EP-3388463-B1 POLYCARBONATE RESIN COMPOSITION FOR THIN OPTICAL COMPONENT, AND METHOD FOR PRODUCING THIN OPTICAL COMPONENT MITSUBISHI CHEM CORP (JP) 2019-10-02 EP disclosed
EP-3388463-A1 POLYCARBONATE RESIN COMPOSITION FOR THIN OPTICAL COMPONENT, AND METHOD FOR PRODUCING THIN OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2018-10-17 EP disclosed
EP-3388465-A1 FLUIDITY MODIFIER FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME Mitsubishi Chemical Corporation (JP) 2018-10-17 EP disclosed
US-20180291146-A1 FLUIDITY MODIFIER FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2018-10-11 US disclosed
US-20180282541-A1 POLYCARBONATE RESIN COMPOSITION FOR THIN OPTICAL COMPONENT, AND METHOD FOR PRODUCING THIN OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2018-10-04 US disclosed
CN-108368249-A Flow modifier for thermoplastic resin and thermoplastic resin composition containing same 三菱化学株式会社 2018-08-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115494-A1 AROMATIC POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME, AND AROMATIC DIHYDROXY COMPOUND SUV39H2, ASH2L, PAH TSHR 4387/4885GABRA1 4145/4885GABRB2 4657/4885
US-11326023-B2 Aromatic polycarbonate resin, method for producing same, and aromatic dihydroxy compound SUV39H2, ASH2L, PAH TSHR 4387/4885GABRA1 4145/4885GABRB2 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.