Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.74 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.74 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.70 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.70 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322345 | 0.88 | DHODH (0.65) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL18118644 | 0.86 | DHODH (0.83) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL18118632 | 0.85 | DHODH (0.77) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL253900 | 0.85 | DHODH (0.80) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL3915164 | 0.84 | DHODH (0.76) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL21371586 | 0.84 | DHODH (1.00) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL31125351 | 0.84 | DHODH (1.00) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| Vidofludimus SCHEMBL247888 | 0.83 | DHODH (1.00) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL20520369 | 0.83 | DHODH (0.72) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| Vidofludimus SCHEMBL29352865 | 0.83 | DHODH (1.00) | DHODHNR4A2NR4A1JMJD7NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110251498-A | One kind adjusts active compound of Farnesoid X receptor and application thereof | 厦门大学 | 2019-09-20 | — | — | CN | claimed |
| WO-2018177151-A1 | COMPOUNDS MODULATING ACTIVITY OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-10-04 | — | — | WO | claimed |