SCHEMBL2052075

SCHEMBL2052075

C=CCC1(C/C=C/CC)C(=O)N(c2ccccc2)N(c2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
PKM P14618 1/20 0.46
ELANE P08246 6/20 0.41
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.38
PGR P06401 2/20 0.37
NPSR1 Q6W5P4 3/20 0.36
GPR55 Q9Y2T6 2/20 0.36
CNR1 P21554 1/20 0.36
RAB9A P51151 1/20 0.33
ABCB11 O95342 1/20 0.33
PTGS1 P23219 1/20 0.33
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052076 1.00 KDM4E (0.46) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2047717 0.89 KDM4E (0.47) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2047716 0.89 KDM4E (0.47) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2043898 0.88 KDM4E (0.47) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2045937 0.87 KDM4E (0.43) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2045934 0.87 KDM4E (0.43) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2051040 0.87 KDM4E (0.51) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2051041 0.87 KDM4E (0.51) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2050826 0.85 KDM4E (0.50) KDM4EPKMELANELMNASMN1; SMN2
SCHEMBL2050824 0.85 KDM4E (0.50) KDM4EPKMELANELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed