Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522143 | 0.78 | — | — | |
| SCHEMBL19635178 | 0.74 | MEN1 (0.31) | KDM4C | |
| SCHEMBL20521691 | 0.72 | NPC1 (0.32) | KDM4C | |
| SCHEMBL31076198 | 0.70 | MEN1 (0.38) | ADORA3KDM4C | |
| SCHEMBL21802183 | 0.69 | MEN1 (0.39) | ADORA3EP300CREBBP | |
| SCHEMBL1912770 | 0.67 | TSHR (0.43) | ADORA3KDM4C | |
| SCHEMBL19635898 | 0.66 | TSHR (0.37) | ADORA3EP300CREBBP | |
| SCHEMBL29601953 | 0.66 | TSHR (0.37) | ADORA3EP300CREBBP | |
| SCHEMBL19615379 | 0.65 | KDM4C (0.39) | ADORA3KDM4C | |
| SCHEMBL19253491 | 0.65 | KDM4C (0.34) | KDM4CEP300CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018178226-A1 | MCL-1 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2018-10-04 | — | — | WO | disclosed |