Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2048832 | 0.92 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2046158 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2054401 | 0.85 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2040621 | 0.82 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2042016 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2043690 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2042044 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2041414 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL6901358 | 0.78 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2038852 | 0.78 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513107-A1 | HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. Lundbeck A/S (DK) | 2012-10-24 | — | — | EP | claimed |
| WO-2011072694-A1 | HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | claimed |