Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037676 | 0.92 | SYK (0.70) | SYK | |
| SCHEMBL2043256 | 0.90 | SYK (0.77) | SYK | |
| SCHEMBL2506093 | 0.88 | SYK (0.70) | SYK | |
| SCHEMBL2015187 | 0.87 | SYK (0.64) | SYK | |
| SCHEMBL2052249 | 0.86 | SYK (0.62) | SYK | |
| SCHEMBL2015704 | 0.83 | SYK (0.77) | SYK | |
| SCHEMBL12194512 | 0.82 | SYK (0.58) | SYK | |
| SCHEMBL2508799 | 0.82 | SYK (0.58) | SYK | |
| SCHEMBL2506930 | 0.82 | SYK (0.58) | SYK | |
| SCHEMBL2035766 | 0.81 | SYK (0.73) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075517-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |