SCHEMBL20523595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18621690	0.87	MAPT (0.51)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL12331687	0.87	MAPT (0.51)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL29373645	0.86	MAPT (0.50)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL2387434	0.86	MAPT (0.50)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL2383479	0.85	MAPT (0.49)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL20522999	0.85	PRKDC (0.40)	MAPTLMNAALDH1A1SMN1; SMN2MEN1
	SCHEMBL18376323	0.84	PDK2 (0.50)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL31111655	0.83	PDK2 (0.48)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL31342252	0.83	PDK2 (0.48)	MAPTLMNAALDH1A1PDK2GPR119
	SCHEMBL19458908	0.82	ALK (0.46)	MAPTLMNAALDH1A1PDK2GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.