⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615128 | 0.84 | — | — | |
| SCHEMBL6631857 | 0.84 | CXCR4 (0.48) | — | |
| Tetradecane SCHEMBL27777921 | 0.83 | CXCR4 (0.49) | — | |
| Ammonia Solution, Strong SCHEMBL27788284 | 0.82 | — | — | |
| SCHEMBL28017309 | 0.82 | — | — | |
| SCHEMBL22871961 | 0.82 | CXCR4 (0.52) | — | |
| SCHEMBL27566558 | 0.81 | — | — | |
| SCHEMBL772696 | 0.80 | — | — | |
| SCHEMBL65385 | 0.80 | — | — | |
| SCHEMBL3635506 | 0.80 | CXCR4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479826-B2 | Pyridazinyl amino derivatives as ALK5 inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-11-25 | — | — | US | disclosed |
| US-20240018122-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-18 | — | — | US | disclosed |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2021027943-A1 | PYRIMIDINOPYRIDAZINONE DERIVATIVE AND MEDICAL USE THEREOF | 正大天晴药业集团南京顺欣制药有限公司 | 2021-02-18 | — | — | WO | disclosed |
| US-10913710-B2 | Benzene disulfonamide for the treatment of cancer | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V (DE) | 2021-02-09 | — | — | US | disclosed |
| US-20200377886-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | US | disclosed |
| EP-3568391-B1 | BENZENE DISULFONAMIDE FOR THE TREATMENT OF CANCER | MAX PLANCK GESELLSCHAFT (DE) | 2020-11-11 | — | — | EP | disclosed |
| CN-110003172-A | The amides containing carbazole, carbamates and ureas as cryptochrome regulator | 同步制药公司 | 2019-07-12 | — | — | CN | disclosed |
| US-20090264612-A1 | ALKOXYSILANE-TERMINATED PREPOLYMERS | WACKER CHEMIE AG (DE) | 2009-10-22 | — | — | US | disclosed |
| WO-2009038031-A1 | BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009038006-A1 | RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-26 | — | — | WO | disclosed |
| US-20080214755-A1 | OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-04 | — | — | US | disclosed |
| WO-2004015039-A1 | NITROGEN COMPOUNDS FOR GAS ODORISATION | SYMRISE GMBH & CO. KG (DE) | 2004-02-19 | — | — | WO | disclosed |
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| CN-1121707-A | Unsaturated amino compounds as anticancer and antiprotozoal agents | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | CN | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |