Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RARA | P10276 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039526 | 0.96 | RARB (0.62) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8971589 | 0.95 | RARB (0.63) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11547222 | 0.94 | RARB (0.64) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11553184 | 0.94 | RARB (0.64) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL13038245 | 0.92 | RARB (0.55) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL13038200 | 0.92 | RARB (0.55) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2020880 | 0.92 | RARB (0.75) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11547608 | 0.92 | RARB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11547226 | 0.92 | RARB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11550115 | 0.92 | RARB (0.60) | RARBMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180291009-A1 | Photochromic Compounds | TRANSITIONS OPTICAL, INC. | 2018-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180291009-A1 | Photochromic Compounds | CCR4, CCR8, CBR3 | RARB 572/4885MAPT 3424/4885SMN1; SMN2 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.