Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528654 | 0.91 | GUSB (0.44) | SMN1; SMN2GUSBEPHX2LMNAMAPT | |
| SCHEMBL20528656 | 0.91 | GUSB (0.44) | SMN1; SMN2GUSBEPHX2LMNAMAPT | |
| SCHEMBL17396832 | 0.82 | HTR2C (0.48) | SMN1; SMN2GUSBAKT1HTR2CLMNA | |
| SCHEMBL20521327 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2GUSBEPHX2AKT1HTR2C | |
| Trifluoromethylbenzene SCHEMBL28601088 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2EPHX2GAAMEN1KMT2A | |
| SCHEMBL30553871 | 0.80 | MEN1 (0.56) | SMN1; SMN2GUSBHTR2CMAPTMEN1 | |
| SCHEMBL17396648 | 0.80 | MEN1 (0.56) | SMN1; SMN2GUSBHTR2CMAPTMEN1 | |
| SCHEMBL20521850 | 0.77 | KMT2A (0.44) | SMN1; SMN2GUSBHTR2CLMNAMAPT | |
| SCHEMBL18815265 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2GUSBAKT1HTR2CMEN1 | |
| SCHEMBL17396661 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2GUSBAKT1HTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184891-A1 | 4-SUBSTITUTED N-AMINO AND N-HYDROXY 2-OXO-PIPERIDINE-3-CARBOXAMIDE DERIVATIVES, SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-11 | — | — | WO | disclosed |