Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529800 | 0.82 | HDAC6 (0.62) | MAPTHDAC6HDAC1HDAC8HPGD | |
| SCHEMBL29627686 | 0.82 | HDAC6 (0.62) | MAPTHDAC6HDAC1HDAC8HPGD | |
| SCHEMBL29966555 | 0.74 | MAPT (0.55) | MAPTHDAC6HDAC1HDAC8HPGD | |
| SCHEMBL20583392 | 0.74 | HDAC6 (0.46) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20550206 | 0.74 | HDAC6 (0.54) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528687 | 0.73 | HDAC6 (0.50) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528693 | 0.73 | HDAC6 (0.49) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20550218 | 0.73 | HDAC6 (0.53) | HDAC6HDAC1HDAC5HDAC8 | |
| Hydrochloric Acid SCHEMBL20528697 | 0.72 | HDAC6 (0.48) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20550566 | 0.72 | HDAC6 (0.52) | HDAC6HDAC1HDAC5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |