Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20448861 | 0.85 | HDAC1 (0.62) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL19053198 | 0.80 | HDAC6 (0.63) | HDAC1HDAC6HDAC8 | |
| SCHEMBL20528691 | 0.77 | HDAC6 (0.47) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29974827 | 0.76 | HDAC1 (0.53) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528673 | 0.75 | HDAC6 (0.45) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20448878 | 0.73 | HDAC6 (0.43) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29362835 | 0.73 | HDAC6 (0.43) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL22076000 | 0.73 | HDAC6 (0.42) | HDAC1HDAC6HDAC8 | |
| SCHEMBL20448905 | 0.71 | HDAC6 (0.70) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL22068852 | 0.70 | HDAC6 (0.57) | HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |