Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 19/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL25367533 | 0.98 | HDAC4 (0.56) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL18609313 | 0.88 | HDAC4 (0.60) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL19100146 | 0.85 | HDAC4 (0.61) | HDAC4HDAC6 | |
| SCHEMBL19100027 | 0.85 | HDAC4 (0.58) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL20528734 | 0.84 | HDAC4 (0.61) | HDAC4HDAC6HDAC1 | |
| SCHEMBL20522006 | 0.84 | HDAC4 (0.54) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL19708947 | 0.84 | HDAC4 (0.56) | HDAC4HDAC6HDAC1 | |
| SCHEMBL18824381 | 0.83 | HDAC4 (0.66) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL20482243 | 0.82 | HDAC4 (0.59) | HDAC4HDAC6HDAC1 | |
| SCHEMBL19047557 | 0.82 | HDAC4 (0.56) | HDAC4HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184982-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |