Dimethyl Succinate

Dimethyl Succinate

SCHEMBL20529591

CCOC(=O)C(=O)OCC.COC(=O)CCC(=O)OC

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
GAA P10253 2/20 0.52
MGAM O43451 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
LMNA P02545 3/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 4/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HTT P42858 1/20 0.45
EGLN1 Q9GZT9 1/20 0.43
MEN1 O00255 1/20 0.43
TRPA1 O75762 1/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA12 O43570 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3007115 0.89 TSHR (0.56) TSHRGAAMGAMSIMGAM2
SCHEMBL1981808 0.87 TSHR (0.68) TSHRGAAMGAMSIMGAM2
SCHEMBL21623621 0.87 GAA (0.62) TSHRGAAMGAMSIMGAM2
Malonic Acid Diethyl Ester SCHEMBL28747435 0.85 GAA (0.75) TSHRGAAMGAMSIMGAM2
Succinic Acid Diethyl Ester SCHEMBL11514685 0.84 GAA (0.57) TSHRGAAMGAMSIMGAM2
Hydrochloric Acid SCHEMBL27634782 0.83 TSHR (0.62) TSHRGAAMGAMSIMGAM2
SCHEMBL11415472 0.82 APOBEC3A (0.51) TSHRGAAMGAMSIMGAM2
SCHEMBL14047450 0.82 TSHR (0.48) TSHRGAAMGAMSIMGAM2
SCHEMBL11415476 0.82 APOBEC3A (0.51) TSHRGAAMGAMSIMGAM2
SCHEMBL129683 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3606979-A1 DIESTER-BASED POLYMER ELECTROLYTES FOR HIGH VOLTAGE LITHIUM ION BATTERIES Seeo, Inc (US) 2020-02-12 EP disclosed
WO-2018186900-A1 DIESTER-BASED POLYMER ELECTROLYTES FOR HIGH VOLTAGE LITHIUM ION BATTERIES SEEO, INC. (US) 2018-10-11 WO disclosed