Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526637 | 1.00 | HRH4 (0.71) | HRH4 | |
| SCHEMBL20526603 | 0.83 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20529932 | 0.82 | HRH4 (0.77) | HRH4 | |
| SCHEMBL20526607 | 0.81 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20526823 | 0.81 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20526539 | 0.79 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20529880 | 0.79 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20526489 | 0.79 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20529871 | 0.77 | HRH4 (1.00) | HRH4 | |
| SCHEMBL20529877 | 0.71 | HRH4 (1.00) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018187652-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-10-11 | — | — | WO | disclosed |