Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 17/20 | 0.91 |
| ▸ | KCNK9 | Q9NPC2 | 17/20 | 0.91 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18963203 | 0.95 | KCNK3 (1.00) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL22364216 | 0.90 | KCNK3 (0.73) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL22260962 | 0.87 | KCNK3 (0.85) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL22260967 | 0.87 | KCNK3 (0.85) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL16261531 | 0.87 | SLC2A1 (1.00) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL18963276 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL18963200 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29458044 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29432778 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL29432726 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386979-A1 | 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-17 | — | — | EP | disclosed |