Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 0.66 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432842 | 0.89 | KCNK3 (0.75) | KCNK3KCNK9 | |
| SCHEMBL18963141 | 0.85 | KCNK3 (0.79) | KCNK3KCNK9 | |
| SCHEMBL30418183 | 0.80 | KCNK3 (0.74) | KCNK3KCNK9 | |
| SCHEMBL18963205 | 0.80 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL22269746 | 0.79 | KCNK3 (0.68) | KCNK3KCNK9 | |
| SCHEMBL18963204 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29458018 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL22269606 | 0.79 | KCNK3 (0.67) | KCNK3KCNK9 | |
| SCHEMBL20531059 | 0.77 | KCNK3 (0.59) | KCNK3KCNK9 | |
| SCHEMBL18963131 | 0.76 | KCNK3 (0.64) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386979-A1 | 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-17 | — | — | EP | disclosed |